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  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/jhg-studies</loc>
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    <lastmod>2026-03-03</lastmod>
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  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/introduction</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-16</lastmod>
    <image:image>
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      <image:title>Introduction</image:title>
      <image:caption>For the purposes of this microsite, adherence and compliance are used interchangeably. If a patient takes a medication as prescribed, the patient is considered adherent. If they do not always follow the prescribed dose, timing, or frequency, they are non-adherent to some degree. Non-adherence can also show up in different patterns, which are described below.</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/3d2bd927-9f6e-4773-9dd3-eb48b53ad4d5/AdobeStock_327067166-LR.jpg</image:loc>
      <image:title>Introduction</image:title>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/b4934b47-34d1-4e63-9626-44731488efbe/AdobeStock_303304617.jpeg</image:loc>
      <image:title>Introduction - MPR (Medication Possession Ratio)</image:title>
      <image:caption>The total days’ supply obtained over a defined period divided by the number of days in that period.  A value of ≥0.8 (80%) is commonly used as the threshold for “adherent.”</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/334766a4-7859-42d3-8156-5003478090dd/MA.jpg</image:loc>
      <image:title>Introduction - PDC (Proportion of Days Covered)</image:title>
      <image:caption>The number of days in which the patient had medication available, divided by the number of days in the period. PDC is generally preferred when patients take multiple therapies for the same condition because it avoids the inflated estimates that can occur with early refills.</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/e1d40f78-e61e-4814-902f-23628fbc9fe5/IntroductionPage_NoSingleMethod.png</image:loc>
      <image:title>Introduction</image:title>
      <image:caption>Indirect methods are more feasible but rely on proxies (fills, openings, self-report).  Some methods capture whether medication was obtained; others capture when it was taken; few capture why doses were missed.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/the-problem</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/595da4fc-918e-4374-9b48-3f2c6e425db4/Diabetes_TheProblemPage.png</image:loc>
      <image:title>The Problem - Diabetes</image:title>
      <image:caption>Non-adherence is associated with higher HbA1c, higher blood pressure, higher LDL cholesterol, increased hospitalization, and increased mortality [2].</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/bd0f6ee8-cfc1-4a66-bc5d-f11abdb08032/Cardio_Disease_TheProblemPage.png</image:loc>
      <image:title>The Problem - Cardiovascular disease</image:title>
      <image:caption>Non-adherence is linked to worse blood pressure control, more cardiac events, and accelerated disease progression [9].</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/a1f7dd1a-aca1-4375-8d42-c7e4d90e2a31/Chronic_Complications-TheProblemPage.png</image:loc>
      <image:title>The Problem - General chronic disease</image:title>
      <image:caption>Non-adherent patients experience higher emergency department use, more frequent inpatient stays, and earlier disease complications [10, 11].</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/9ed3f085-0f87-44e3-9f28-b6a01ee0b024/Non-Adherence-2.png</image:loc>
      <image:title>The Problem - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/737fdbcb-37b7-4b3f-8dc1-61b14a15f0ef/Improving_Adherence.jpg</image:loc>
      <image:title>The Problem</image:title>
      <image:caption>Better disease control  Fewer complications  Reduced hospitalizations  Lower overall system costs</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/the-pharmacists-role</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/3afbd5f9-55bf-4a82-af2b-21f9736ac075/AdobeStock_266557688.jpeg</image:loc>
      <image:title>The Pharmacist's Role - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/130e7451-4040-4939-bc09-31d4dc43cf15/ThePharmacistsRole-Section.png</image:loc>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/a9c4713f-2134-4e6d-9590-0aaf7aaa9184/AdobeStock_255759509.jpg</image:loc>
      <image:title>The Pharmacist's Role - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/summary</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/18c360d0-0697-4eb4-9a34-4847d08bb2dc/Summary_BlisterPackaging.png</image:loc>
      <image:title>Summary - Impact varies by population,</image:title>
      <image:caption>but blister packaging reliably outperforms vial dispensing and simple pill organizers—particularly when professionally prepared, calendarized, or paired with pharmacist follow-up [14,19,22].</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/2f31f6c7-685d-4000-b112-74fc42abe654/FlexRx%26Qube-Group-Summary.jpg</image:loc>
      <image:title>Summary - Eco-Friendly, Patient-Centred Blister Packaging</image:title>
      <image:caption>Jones’ adherence packaging solutions are designed around patient safety, pharmacy workflow, and sustainability:  Recyclable card stock and bio-based recyclable plastics – formats are developed using a recyclable-first design philosophy aligned with evolving sustainability expectations in healthcare systems.  Compatible with both manual and automated filling systems  Clear, intuitive graphics for safe patient use  Available in multiple formats and blister sizes for unit- or multi-dose dispensing</image:caption>
    </image:image>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/5a72b260-caea-42b9-9ec0-6a0f1658908f/Jones_Cpax_GroupPhoto_2.jpg</image:loc>
      <image:title>Summary - Make it stand out</image:title>
      <image:caption>The CpaX™ Connected Medication Adherence Platform offers two types of intelligent blister packs.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/blister-pack-data</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/adherence-packaging</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/2832421f-5a64-43f8-838c-ff064052ebec/AdobeStock_204671872.jpg</image:loc>
      <image:title>Adherence Packaging - Pill organizers can support routine but offer no safety check and rely fully on the patient’s ability to fill and manage them correctly.</image:title>
      <image:caption>Example of a pill organizer</image:caption>
    </image:image>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/03ce7fc9-ca04-4508-bfad-20d9b086fcd6/NIK_2277.jpg</image:loc>
      <image:title>Adherence Packaging - Make it stand out</image:title>
      <image:caption>Unit-dose adherence packaging</image:caption>
    </image:image>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/462aa571-0fa9-4054-b4df-bbb2b67e3385/NIK_2256.jpg</image:loc>
      <image:title>Adherence Packaging - Make it stand out</image:title>
      <image:caption>Multi-dose adherence packaging</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/25237fb1-4de5-4bd1-a785-d2a22cb6f655/BlisterPackaging_AdherencePackaging.png</image:loc>
      <image:title>Adherence Packaging - Studies show blister packaging improves adherence measurements such as MPR and reduces dosing errors, particularly for older adults and those with cognitive challenges [14,15].</image:title>
    </image:image>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/de09db6b-05a7-4146-991c-3670315a5260/NIK_3120-2_green.jpg</image:loc>
      <image:title>Adherence Packaging - These devices support refill-level adherence insights but do not verify ingestion.</image:title>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/d1c08ba0-7bcc-4fe3-b9de-0e95b8cdf69b/AdherencePackaging_Blister_Close-UpSaturated.png</image:loc>
      <image:title>Adherence Packaging - Smart blister packaging transforms a passive package into an active support tool for patients and care teams.</image:title>
      <image:caption>Smart blister packaging transforms a passive package into an active support tool for patients and care teams.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/97226242-e411-4880-b4b8-e848595f9610/JHG_CpaX-NFC-Connected-Packaging.jpg</image:loc>
      <image:title>Adherence Packaging - Unlike smart blister packs, NFC systems require patient action but remain a highly affordable pathway to digital readiness.</image:title>
    </image:image>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/error-404</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2022-06-24</lastmod>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/contact</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-11</lastmod>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/academic-references</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-13</lastmod>
  </url>
  <url>
    <loc>https://adherence-studies.joneshealthcaregroup.com/the-solution-for-non-adherence</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2025-12-16</lastmod>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/626fcd617884513d93522dbb/85af27da-4090-4137-88fb-f4c273e93c71/TheSolution_PharmacyLed.png</image:loc>
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